Berkeley Lab
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Deciphering the Impact of Non-coding Mutations in the Human Genome

Biosciences Area researchers have developed a higher-throughput transgenic mouse assay to evaluate the disease-causing potential of human variants in enhancers, which are regulatory switches found in the non-coding sequence that control when and where genes are turned on or off in an organism. https://biosciences.lbl.gov/2020/03/25/deciphering-the-impact-of-non-coding-mutations-in-the-human-genome/

Lab Computing Power Applied to COVID-19 Crisis

NERSC is contributing resources to the COVID-19 High-Performance Computing Consortium, and ESnet is the network for the consortium. NERSC has dedicated queues running COVID-19-related research projects on Cori, a Cray XC40 supercomputer able to perform nearly 30 quadrillion calculations per second. https://cs.lbl.gov/news-media/news/2020/nersc-esnet-continue-to-deliver-supercomputing-networking-support-for-nations-scientists-during-pandemic/