Biosciences Area researchers have developed a higher-throughput transgenic mouse assay to evaluate the disease-causing potential of human variants in enhancers, which are regulatory switches found in the non-coding sequence that control when and where genes are turned on or off in an organism. https://biosciences.lbl.gov/2020/03/25/deciphering-the-impact-of-non-coding-mutations-in-the-human-genome/
January 2019 – July 2022
